Impotence Induced by a Single Gene Mutation1

Impotence: treatment by autoinjection of vasoactive drugs.

One hundred and twenty five men with psychogenic or organic impotence used autoinjection of the penile corpora cavernosa with either papaverine or papaverine and phentolamine for a mean period of 10.5 months (range 1-24 months) to achieve penile erection for sexual intercourse. Prolonged (over four hours) painless erection resulted from 34 of the 3513 self administered injections. This seems to...

Sexual Impotence

P-85: How a Frame Shift Caused by a Single Base Deletion In SEPT12 Gene Shed Lights As a Polymorphism

Background: Septins are members of highly conserved polymerizing GTP binding proteins well described in the animal kingdom. 14 Septin proteins have been characterized in humans (SEPT1-SEPT14), some of which are tissue-specific. All of 14 genome-mapped human septins contain a highly conserved central GTP-binding domain which is very critical in GTPase signaling properties as well as oligomerizat...

Managing impotence in diabetes.

Should be part ofa diabetes care service Erectile impotence affects over one third of diabetic men.' Effective treatments have been available for over a decade, yet it remains the most neglected complication of diabetes. It is not discussed in the British Diabetic Association's current guidelines for diabetes care2 or in its recent proposals for the audit of diabetes services.3 Most impotent me...

Hydralazine and Male Impotence

CHEST, 78: 2, AUGUST, 1980 edema, pseudocyst formation or development of fibrous penpancreatic adhesions may all lead to obstruction of the intestinal lymphatics as they converge into the root of the mesentery in the region of the uncinate process of the pancreas and cause chylous ascites.’ The association of chylous ascites and chylothorax has been documented.’ Intraperitoneal injection of con...